病理诊所中癌症的诊断，预后和治疗性决策现在可以基于对多吉吉像素组织图像的分析，也称为全斜图像（WSIS）。最近，已经提出了深层卷积神经网络（CNN）来得出无监督的WSI表示。这些很有吸引力，因为它们不太依赖于繁琐的专家注释。但是，一个主要的权衡是，较高的预测能力通常以解释性为代价，这对他们的临床使用构成了挑战，通常通常期望决策中的透明度。为了应对这一挑战，我们提出了一个基于Deep CNN的手工制作的框架，用于构建整体WSI级表示。基于有关变压器在自然语言处理领域的内部工作的最新发现，我们将其过程分解为一个更透明的框架，我们称其为手工制作的组织学变压器或H2T。基于我们涉及各种数据集的实验，包括总共5,306个WSI，结果表明，与最近的最新方法相比，基于H2T的整体WSI级表示具有竞争性能，并且可以轻松用于各种下游分析任务。最后，我们的结果表明，H2T框架的最大14倍，比变压器模型快14倍。

计算病理（CPATH）是一种具有关于组织病理研究的新兴领域，通过计算和分析组织载玻片的数字化高分辨率图像的处理算法。CPATH最近的深度学习的发展已经成功地利用了组织学图像中的原始像素数据的纯粹体积，以预测诊断域，预测，治疗敏感性和患者分层中的目标参数 - 覆盖新数据驱动的AI时代的承诺既组织病理学和肿瘤。使用作为燃料和作为发动机的燃料和AI的数据，CPATH算法准备好用于起飞和最终发射到临床和药物轨道中。在本文中，我们讨论了CPATH限制和相关挑战，使读者能够区分HIPE的希望，并为未来的研究提供指示，以克服这个崭露头角领域的一些主要挑战，以使其发射到两个轨道上。

This paper presents our solutions for the MediaEval 2022 task on DisasterMM. The task is composed of two subtasks, namely (i) Relevance Classification of Twitter Posts (RCTP), and (ii) Location Extraction from Twitter Texts (LETT). The RCTP subtask aims at differentiating flood-related and non-relevant social posts while LETT is a Named Entity Recognition (NER) task and aims at the extraction of location information from the text. For RCTP, we proposed four different solutions based on BERT, RoBERTa, Distil BERT, and ALBERT obtaining an F1-score of 0.7934, 0.7970, 0.7613, and 0.7924, respectively. For LETT, we used three models namely BERT, RoBERTa, and Distil BERTA obtaining an F1-score of 0.6256, 0.6744, and 0.6723, respectively.

In recent years, social media has been widely explored as a potential source of communication and information in disasters and emergency situations. Several interesting works and case studies of disaster analytics exploring different aspects of natural disasters have been already conducted. Along with the great potential, disaster analytics comes with several challenges mainly due to the nature of social media content. In this paper, we explore one such challenge and propose a text classification framework to deal with Twitter noisy data. More specifically, we employed several transformers both individually and in combination, so as to differentiate between relevant and non-relevant Twitter posts, achieving the highest F1-score of 0.87.

Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In this work, we propose a novel framework called SynCLay (Synthesis from Cellular Layouts) that can construct realistic and high-quality histology images from user-defined cellular layouts along with annotated cellular boundaries. Tissue image generation based on bespoke cellular layouts through the proposed framework allows users to generate different histological patterns from arbitrary topological arrangement of different types of cells. SynCLay generated synthetic images can be helpful in studying the role of different types of cells present in the tumor microenvironmet. Additionally, they can assist in balancing the distribution of cellular counts in tissue images for designing accurate cellular composition predictors by minimizing the effects of data imbalance. We train SynCLay in an adversarial manner and integrate a nuclear segmentation and classification model in its training to refine nuclear structures and generate nuclear masks in conjunction with synthetic images. During inference, we combine the model with another parametric model for generating colon images and associated cellular counts as annotations given the grade of differentiation and cell densities of different cells. We assess the generated images quantitatively and report on feedback from trained pathologists who assigned realism scores to a set of images generated by the framework. The average realism score across all pathologists for synthetic images was as high as that for the real images. We also show that augmenting limited real data with the synthetic data generated by our framework can significantly boost prediction performance of the cellular composition prediction task.

Temporal data like time series are often observed at irregular intervals which is a challenging setting for existing machine learning methods. To tackle this problem, we view such data as samples from some underlying continuous function. We then define a diffusion-based generative model that adds noise from a predefined stochastic process while preserving the continuity of the resulting underlying function. A neural network is trained to reverse this process which allows us to sample new realizations from the learned distribution. We define suitable stochastic processes as noise sources and introduce novel denoising and score-matching models on processes. Further, we show how to apply this approach to the multivariate probabilistic forecasting and imputation tasks. Through our extensive experiments, we demonstrate that our method outperforms previous models on synthetic and real-world datasets.

具有多吉吉像素的组织学图像产生了丰富的信息，以用于癌症诊断和预后。在大多数情况下，只能使用幻灯片级标签，因为像素的注释是劳动密集型任务。在本文中，我们提出了一条深度学习管道，以进行组织学图像中的分类。使用多个实例学习，我们试图预测基于降血石蛋白和曙红蛋白（H＆E）组织学图像的鼻咽癌（NPC）的潜在膜蛋白1（LMP1）状态。我们利用了与聚合层保持剩余连接的注意机制。在我们的3倍交叉验证实验中，我们分别达到了平均准确性，AUC和F1得分为0.936、0.995和0.862。这种方法还使我们能够通过可视化注意力评分来检查模型的可解释性。据我们所知，这是使用深度学习预测NPC上LMP1状态的首次尝试。

从不同扫描仪/部位的有丝分裂数字的检测仍然是研究的重要主题，这是由于其潜力协助临床医生进行肿瘤分级。有丝分裂结构域的概括（MIDOG）2022挑战旨在测试从多种扫描仪和该任务的多种扫描仪和组织类型中看不见数据的检测模型的鲁棒性。我们提供了TIA中心团队采用的方法来应对这一挑战的简短摘要。我们的方法基于混合检测模型，在该模型中，在该模型中进行了有丝分裂候选者，然后被深度学习分类器精炼。在训练图像上的交叉验证在初步测试集上达到了0.816和0.784的F1得分，这证明了我们模型可以从新扫描仪中看不见的数据的普遍性。

组织病理学图像的出现取决于组织类型，染色和数字化过程。这些因素因来源而异，是域转移问题的潜在原因。由于这个问题，尽管深度学习模型在计算病理学中取得了巨大的成功，但在特定领域训练的模型当我们将其应用于另一个领域时，仍可能会表现出色。为了克服这一点，我们提出了一种称为PatchShuffling的新扩展，并为预训练的深度学习模型而被称为Impash的新型自我监视的对比学习框架。使用这些，我们获得了一个RESNET50编码器，该编码器可以提取对域移位抗性的图像表示。我们通过使用其他域普通化技术来比较了我们的派生表示形式，它们通过将它们用于结直肠组织图像的跨域分类。我们表明，所提出的方法优于其他传统的组织学领域适应和最先进的自我监督学习方法。代码可在以下网址获得：https：//github.com/trinhvg/impash。

多媒体分析，计算机视觉（CV）和人工智能（AI）算法的最新进步导致了几种有趣的工具，允许自动分析和检索用户利益的多媒体内容。但是，检索感兴趣的内容通常涉及语义特征的分析和提取，例如情感和兴趣级别。这种有意义的信息的提取是一项复杂的任务，通常，单个算法的性能非常低。增强单个算法性能的一种方法是使用融合方案结合多种算法的预测能力。这使各个算法可以相互补充，从而提高了性能。本文提出了有关媒体趣味性得分预测任务的几种融合方法。CLEFFusion 2022中引入了。所提出的方法既包括一个天真的融合方案，其中所有诱导剂均得到同等处理和基于功绩的融合方案，其中采用了多重重量优化方法为单个诱导者分配权重。我们总共使用了六种优化方法，包括粒子群优化（PSO），遗传算法（GA），Nelder Mead，信任区域约束（TRC）和有限的MEMORY BROYDEN FLECHER GOLDFARB SHANNO SHANNO算法（LBFGSA）以及截断的牛顿牛顿算法（TNA）。总体而言，通过PSO和TNA达到0.109的平均平均精度为10。任务是复杂的，通常得分很低。我们认为，提出的分析将为未来在领域的研究提供基准。